Basal Ganglia Research Group

University of Otago

Prof John Reynolds, PI

MBChB, PhD (Otago)

John gained a degree in Medicine in 1994 and completed a PhD in Neuroscience in 2000.

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Dr Nico Vautrelle, Assistant Research Fellow

PhD (Lyon, France)

 

Nico completed his PhD in Lyon, France, where he studied the electrophysiological activity of several Basal Ganglia nuclei on a model of Parkinson’s Disease.

Over the past 10 years, Nico’s research interest focused on understanding the role of the Basal Ganglia in decision making and reinforcement learning.

He is now working in establishing a new model of Parkinson’s disease in the Reynolds Lab with the aim of developing new therapeutic technologies that would translate in new therapeutic strategies for humans.

He commonly uses stereotaxic surgery, behavioral testing, in vitro and in vivo electrophysiology and immunohistochemistry for his research and is learning high-performance liquid chromatography.

Jason Gray, Assistant Research Fellow

Dip. Grad (Otago), MSc (Otago)

 

Jason has been an ARF in the Anatomy Department since 2010. Having previously worked for AgResearch for over a decade, he has competency in a range of techniques. Currently he is involved in a project to develop an on-demand drug delivery system for the brain with potential application in treating conditions such as Parkinson’s and epilepsy.

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Dr Laura Boddington, Assistant Research Fellow

BSc (Hons), PHD (Otago)

 

Laura is interested in understanding the cortical circuitry involved in interhemispheric communication in the brain, and how this is altered after stroke. Laura completed her BSc(Hons) and PhD projects in the Reynolds lab investigating the functional and electrophysiological effects of applying electrical stimulation to the brain following stroke. Laura has experience in in vivo sharp electrode electrophysiology, behavioural assessments of motor function, and is currently working towards establishing in vivo whole-cell patch clamp recording in the lab. 

Natalie Matheson, Postdoctoral Fellow

BSc, PGDipSci(Neuroscience)

 

Natalie joined the lab in 2012 to begin a PhD investigating the effects of transcranial magnetic stimulation on single neuron activity within the brain. In 2017 Natalie will begin a postdoctoral fellowship in the lab, building on the work of her PhD to examine how magnetic stimulation alters the activity of neurons in the stroke-damaged brain.

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Matthew Sykes, PhD Candidate

MBiol (hons)

Matthew started in the lab in 2012 as a PhD student on a collaborative project between two institutions of the Matariki network: University of Otago and University of Western Australia. He is interested in network and population dynamics and their response to non-invasive brain stimulation. Matthew's PhD has focussed on the ability for low-intensity pulsed magnetic fields to impact local excitability using intra-cortical measures. MBiol (hons)

Dr Joyce Lim, MMedSci Student

Joyce completed her Medicine degree from Ireland in 2011 and is currently doing a MMedSci with Professor John Reynolds and Professor Dirk De Ridder. She is investigating the use of neuromodulation in a translational stroke study in human beings.

Rosie Melchers, PhD (intercalated) Student

Rosie is a medical student at the University of Otago, currently completing the work required for an intercalated PhD. She joined the lab as a BMedSci student in 2016 and is looking at using electrical stimulation techniques to measure and modify how the hemispheres of the brain communicate after motor cortex stroke.

Annabel Kean, Research Assistant

MSc (Otago)

 

Annabel works part time for Prof Reynolds, assisting in administrative and research support.